GPAT Question Paper 2010

About this paper

This is a scanned copy of the Graduate Pharmacy Aptitude Test (GPAT) 2010 question paper, with an answer key on the last page. It has 100 multiple-choice questions with four options each, in one continuous run with no sections; marks, time and negative marking are not printed. The questions move between pharmacognosy (aloe, quassia, guggul, Lycopodium spore counts), pharmacology, medicinal chemistry, pharmaceutical analysis and biochemistry, then pharmaceutics, cosmetics, pharmacokinetics and the Drugs and Cosmetics Act. A few are calculations on alcohol dilution, stock solutions, bioavailability, volume of distribution and sustained-release dosing.

Exam

GPAT

Subject

GPAT

Year

2010

Questions

100

Pages

9

Answers included

Yes

Topics covered

• Pharmacognosy and phytochemistry
• Pharmacology and chemotherapy
• Medicinal chemistry and drug synthesis
• Spectroscopy and chromatography
• Biochemistry
• Pharmaceutics and tablet formulation
• Cosmetic formulations
• Biopharmaceutics and pharmacokinetics
• Pharmaceutical calculations
• Drugs and Cosmetics Act and Pharmacy Council

Questions from this paper

1. How many mL of a 1:500 w/v stock solution should be used to make 5 litres of a 1:2000 w/v solution?
2. A drug given as a 200 mg tablet and as a 50 mg intravenous injection showed AUCs of 100 and 200 µg·h/mL respectively. What is the absolute bioavailability of the oral dose?
3. Which monoclonal antibody is prescribed for patients with non-Hodgkin's lymphoma?
4. What is the common structural feature of the barbiturate, succinimide and hydantoin classes of anticonvulsants?
5. Which HPLC detector is most sensitive to changes in temperature?
6. In the Drugs and Cosmetics Act and Rules, which Schedule relates to Good Manufacturing Practices?